Distribution of nosocomial infections caused by Klebsiella pneumoniaeESBL strain

Abstract

Sadeta HadžiÄ?,AmerÄ?ustoviÄ?, Jasmina SmajloviÄ?, Sead AhmetagiÄ?

Objectives: Hospital outbreaksof multidrug-resistant Klebsiella species, especially those in neonatalwards, are often caused by new types ofstrains, the so-calledextended-spectrum-β-lactamase (ESBL) producers. Methods: The aim of this study was to determine the distribution of nosocomial infections caused by Klebsiella pneumoniaeESBL strain by location and kind of infections on the University ClinicalCenterTuzla during a period of one year. A prospective study was implemented for all patients who developed hospital infections caused by Klebsiella pneumoniaeESBL strain during the period from the 1stof January to 31stof December 2010. Determination of nosocomial infections was performed using standardized Centers for Disease Control (CDC) criteria. Mandatory registration of hospital infections was done via a written application form which was used for surveillance.Results: Hospital infections caused by Klebsiella pneumoniaeESBL strain were reported 141 times, during the year 2010.Most common hospital infections were urinary tract infections 52 times (36.9%), followed by respiratory tract infections 43 times (30.5%), infections of the gastrointestinal system 20 times (14.2%), infections of surgical sites 12 times (8.5%), 10 times (7.1%) the bloodstream infections and other infections 4 times (2.8%). Nosocomial infection was mostly reported on the Clinicof Anesthesiology and Reanimation 37 times (26.2%) and the Clinic for Children's Diseases 33 times (23.4%). Regarding age, 41 (29.1%) of nosocomial infections were detected in patients below the age of one year and 35 (24.8%) in patients above the age of 65 years. Conclusion: It is necessary to continue to monitor occurrence and the distribution of nosocomial infections caused by Klebsiella pneumoniase ESBL strain in order to find solutions to their reduction and prevention